Andrology & Sexual Medicine

A 56-year-old with new erectile dysfunction (ED) and multiple cardiovascular risk factors; best initial approach?

A man on nitrates for angina asks about sildenafil; appropriate advice?

Which adverse effect is most characteristic of sildenafil vs other PDE5 inhibitors?

Mechanism of erection most directly enhanced by PDE5 inhibitors?

Patient on tamsulosin wants tadalafil; safe strategy?

Which medication is most associated with QT prolongation risk among PDE5 inhibitors?

Duplex penile Doppler after ICI shows PSV 18 cm/s bilaterally with EDV 0–2 cm/s; interpretation?

Which duplex Doppler pattern suggests veno-occlusive dysfunction (venous leak)?

First-line pharmacologic therapy for most ED not due to reversible medication effect?

Key counseling for sildenafil dosing?

A 29-year-old with sudden painful rigid erection after trazodone; next best step?

In suspected nonischemic (high-flow) priapism after perineal trauma, a distinguishing feature is:

Initial management for stuttering priapism in sickle cell disease includes:

After 6 hours of ischemic priapism unresponsive to phenylephrine and aspiration, next step?

Peyronie’s disease in the acute painful phase with new 45° curvature and good erections; best initial plan?

Indication for intralesional collagenase Clostridium histolyticum (CCH) in Peyronie’s disease?

Surgical option preferred for Peyronie’s with stable 35° curvature and rigid erections desiring straightening?

In Peyronie’s with severe curvature >60° and significant length loss but preserved rigidity, best surgical approach?

Post-prostatectomy ED early rehabilitation strategy includes:

Which statement about vacuum erection devices (VED) is correct?

Most definitive treatment for refractory venogenic ED (true venous leak) with poor PDE5/ICI response?

Before starting testosterone therapy, which is required?

Which is an absolute/strong contraindication to testosterone therapy?

Monitoring on testosterone therapy should include:

A 33-year-old desires fertility but has symptomatic hypogonadism with low T and low LH/FSH. Best therapy?

Most common medication class causing delayed ejaculation/anorgasmia?

First-line therapy for lifelong premature ejaculation?

A 45-year-old with ED and exertional angina not yet evaluated by cardiology; next step?

Which lifestyle change has the strongest evidence for improving ED?

A 22-year-old with normal spontaneous erections but situational ED; initial management?

Which post-RP factor best predicts response to PDE5 inhibitors?

A man on chronic opioids has low libido and ED; likely endocrine issue?

Workup for suspected hyperprolactinemia-related ED should include:

After intracavernosal alprostadil teaching, key safety instruction is to:

Which condition is an indication for malleable rather than inflatable penile prosthesis?

Typical ultrasound finding in penile fracture?

Suspected urethral injury with penile fracture presents with:

Which adverse effect is most specific to tadalafil vs sildenafil?

ED in diabetes is driven primarily by:

Best diagnostic test to differentiate psychogenic from organic ED when history is unclear?

Which Peyronie’s plaque location is a contraindication to intralesional collagenase (CCH) per labeling?

When measuring total testosterone for hypogonadism evaluation, the optimal timing is:

PDE5 inhibitor “nonresponder” counseling should include:

Which is a strong contraindication to initiating testosterone therapy?

Compared with transdermal gels, long‑acting injectable testosterone more commonly causes:

First‑line pharmacologic agent for ischemic priapism after aspiration/irrigation is:

A risk factor for penile prosthesis infection is:

Timing of surgical repair for penile fracture is best described as:

Appropriate antibiotic strategy for inflatable penile prosthesis placement includes:

A patient with ED and marked hyperprolactinemia should receive:

The on‑demand SSRI with the fastest onset and shortest half‑life for premature ejaculation (where available) is:

A frequent medication cause of delayed ejaculation is:

Optimal timing for post‑alprostadil penile duplex Doppler measurements is:

After prostate radiotherapy, ED pathophysiology is primarily:

A common adverse effect of testosterone therapy that requires monitoring and dose adjustment is:

Testosterone can aromatize to estradiol leading to which side effect?

A man with Klinefelter syndrome (47,XXY) most commonly has:

Which PDE5 inhibitor has the longest half‑life allowing “weekend” dosing?

A normal nocturnal penile tumescence/rigidity (NPT) study suggests:

Components of “Trimix” for intracavernosal injection are typically:

The most common adverse effect of alprostadil ICI monotherapy is:

A drawback of vacuum erection device (VED) use is:

After CCH injections for Peyronie’s, key safety counseling includes:

In obesity or altered SHBG states with borderline total testosterone, next best lab is:

Which additional lab is reasonable in low libido with ED when initial T is normal?

Among antihypertensives, which carry higher ED risk?

A cyclist with numb perineum and ED likely has:

Substance associated with ischemic priapism episodes:

After stopping exogenous testosterone, spermatogenesis typically recovers over:

For hypogonadal men desiring fertility, a medical alternative to TRT is:

A patient reports inability to achieve orgasm despite adequate erections; first‑line management?

In Peyronie’s with severe ED refractory to meds, best surgical choice is:

Hematospermia in a healthy man <40 years with normal exam and UA should be managed by:

Chronic pelvic pain syndrome (CP/CPPS) often impacts sexual function; helpful multimodal approach includes:

An SSRI‑treated patient with low libido seeks options; reasonable strategy is:

In spinal cord injury, erectile function is most responsive to PDE5 inhibitors when:

A typical lower limit of normal for adult male total testosterone (varies by lab) is around:

Candidate profile for penile arterial revascularization surgery is:

Counseling for tadalafil daily 5 mg includes:

Key difference between organic and psychogenic ED on history is:

Which is an absolute contraindication to initiating testosterone replacement therapy?

A man reports little to no semen with orgasm after starting an alpha-blocker; best diagnostic test?

Which PDE5 inhibitor has the fastest onset with less food effect, suitable for on‑demand use?

Which medication most commonly causes anejaculation/retrograde ejaculation as an adverse effect?